SigInt 1.0

SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes.
SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.

The inputs to the program are: (a) a seed list of human Entrez Gene gene symbols, (b) a background networks in SIG format, and (c) a name for the output file (web-page file name with the htm extension). SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.

SigInt can be run on Linux, Mac and Windows operating systems and it requires a background network text file in SIG format.

Usage:

Extract the archive
chmod +x sigint_lnx.exe
./sigint_lnx.exe

last updated on:
February 15th, 2007, 18:40 GMT
price:
FREE!
developed by:
Mount Sinai School of Medicine.
homepage:
amp.pharm.mssm.edu
license type:
Freeware 
category:
ROOT \ Science and Engineering \ Medical Science Apps.

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