SigInt 1.0

SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes.

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LICENSE TYPE:
Freeware 
USER RATING:
2.1/5 20
DEVELOPED BY:
Mount Sinai School of Medicine.
HOMEPAGE:
amp.pharm.mssm.edu
CATEGORY:
ROOT \ Science and Engineering \ Medical Science Apps.
1 SigInt Screenshot:
SigInt
SigInt project is a command-line software tool that can be used to find and rank mammalian proteins/genes that specifically and significantly interact with a list of proteins/genes in context of a background mammalian signalome and interactome networks.

The inputs to the program are: (a) a seed list of human Entrez Gene gene symbols, (b) a background networks in SIG format, and (c) a name for the output file (web-page file name with the htm extension). SigInt outputs a sorted list of genes/proteins that interacts with components from the seed list. These components are sorted by a z-score that measures the specificity of these intermediate components to interact with the genes/proteins from the seed list.

SigInt can be run on Linux, Mac and Windows operating systems and it requires a background network text file in SIG format.

Usage:

Extract the archive
chmod +x sigint_lnx.exe
./sigint_lnx.exe

Last updated on February 15th, 2007

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