ThermonucleotideBLAST 1.05

ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences.

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LICENSE TYPE:
GPL (GNU General Public License) 
USER RATING:
2.3/5 19
DEVELOPED BY:
Jason D. Gans
HOMEPAGE:
public.lanl.gov
CATEGORY:
ROOT \ Science and Engineering \ Bioinformatics
3 ThermonucleotideBLAST Screenshots:
ThermonucleotideBLASTThermonucleotideBLASTThermonucleotideBLAST
ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences using an assay specific query that is based on biochemical assays (i.e. a pair of oligonucleotide sequences representing PCR primers or Padlock probes, a triplet of oligos representing PCR primers and a TaqMan probe, or a single oligo representing a hybridization probe).

Unlike existing programs like BLAST, which use heuristic measures of sequence similarity for identifying matches between a query and target sequence, ThermonucleotideBLAST uses free energy and melting temperature.

What's New in This Release:

This update features a significant rewrite of thermodynamic alignment algorithm, including the addition of the Dinkelbach fractional programming algorithm for computing duplex melting temperatures.

Last updated on May 25th, 2008

#database search #nucleic acid sequences #database query #nucleic #acid #sequences #database

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