ThermonucleotideBLAST 1.05

ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences.
ThermonucleotideBLAST
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ThermonucleotideBLAST is an application for searching a target database of nucleic acid sequences using an assay specific query that is based on biochemical assays (i.e. a pair of oligonucleotide sequences representing PCR primers or Padlock probes, a triplet of oligos representing PCR primers and a TaqMan probe, or a single oligo representing a hybridization probe).

Unlike existing programs like BLAST, which use heuristic measures of sequence similarity for identifying matches between a query and target sequence, ThermonucleotideBLAST uses free energy and melting temperature.

What's New in This Release:

This update features a significant rewrite of thermodynamic alignment algorithm, including the addition of the Dinkelbach fractional programming algorithm for computing duplex melting temperatures.

last updated on:
May 25th, 2008, 22:39 GMT
price:
FREE!
developed by:
Jason D. Gans
homepage:
public.lanl.gov
license type:
GPL (GNU General Public License) 
category:
ROOT \ Science and Engineering \ Bioinformatics
ThermonucleotideBLAST
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