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An Open Source software synthesizer that's capable of simulating numerous instruments
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A realtime modular synthesizer and effect processor
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ppc is a remote and SysEx-editor for E-MU Planet Phatt, Carnaval and Orbit devices.
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nonlimitedSynth is a backend to reacTIVision.
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PADsynth is an audio synthesizer using Mammut FFT.
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TiMidity++ is a software synthesizer.
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Spiral Synth Modular is a cool and expandable modular synthesizer.